ACS Pharmacology and Translational Science

Characterization of the Cross-Resistance of SARS-CoV‑2 Main Protease Inhibitors, Ibuzatrelvir, Ensitrelvir, and Nirmatrelvir.

Beneficial Effects of a Novel Fructose-1,6-Bisphosphatase Inhibitor Cpd96 on Insulin Secretion in Type 2 Diabetes.

Ponatinib Averts αCD40 Antibody Mediated Toxicity by Lowering MAPK38 Expression and Shows Proimmunogenic Effects in a Murine Tumor Model

Ponatinib通过降低MAPK38表达来避免αCD40抗体介导的毒性，并在小鼠肿瘤模型中显示出促免疫原性作用。

Targeting Metabolic Vulnerabilities Reveals Hexokinase 2 as a Key Mediator of Resistance to Osimertinib in Non-Small Cell Lung Cancer Models

靶向代谢脆弱性揭示己糖激酶2是非小细胞肺癌模型中奥希替尼耐药的关键介质

Antineuroblastoma Activity Evaluation and Mechanism of Novel PD-L1 Small Molecule Inhibitors through Immune and Non-Immune Pathways

新型PD-L1小分子抑制剂通过免疫和非免疫途径发挥抗神经母细胞瘤活性及机制的研究

Relaxin-2 Exhibits a Beneficial Role in Energy Metabolism to Alleviate Atrial Fibrillation Susceptibility

松弛素-2在能量代谢中发挥有益作用，可减轻心房颤动易感性

Oxidative Stress-Responsive 1 Kinase Catalytic Activity Promotes Triple Negative Breast Cancer Oncogenic Potential.

氧化应激反应 1 激酶催化活性促进三阴性乳腺癌的致癌潜能。

Synthesis, Characterization, Interactions, and Immunomodulatory Function of Ectonucleotidase CD39/CD73 Inhibitor 8-Butylthioadenosine 5'-Monophosphate.

胞外核苷酸酶 CD39/CD73 抑制剂 8-丁硫代腺苷 5'-单磷酸的合成、表征、相互作用和免疫调节功能。

Surface Plasmon Resonance Imaging-Based Platform Enables Detection of Single, Site-Specific 5-Methylcytosine Associated with Post-traumatic Stress Disorder (PTSD).

基于表面等离子体共振成像的平台能够检测与创伤后应激障碍 (PTSD) 相关的单个位点特异性 5-甲基胞嘧啶。

Enzymatic Desialylation Enables Reliable Charge Variant Characterization of Highly Glycosylated and Sialylated Fc Fusion Proteins.

酶促去唾液酸化可实现对高度糖基化和唾液酸化的Fc融合蛋白的可靠电荷变体表征。