The Small Molecule Antagonist KCI807 Disrupts Association of the Amino-Terminal Domain of the Androgen Receptor with ELK1 by Modulating the Adjacent DNA Binding Domain
小分子拮抗剂KCI807通过调节邻近的DNA结合域,破坏雄激素受体氨基末端结构域与ELK1的结合。
期刊:Mol Pharmacol
影响因子:3.200
doi:10.1124/molpharm.122.000589
Claire Soave ,Charles Ducker ,Naeyma Islam ,Seongho Kim ,Sally Yurgelevic ,Nathan I Nicely ,Luke Pardy ,Yanfang Huang ,Peter E Shaw ,Gregory Auner ,Alex Dickson ,Manohar Ratnam