Blood Cancer Discovery

Endogenous CD28 drives the persistent activity of CAR T cells in myeloma and lymphoma models.

Tandem Duplications in UBTF Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency.

Clinical and Cytokine Features of Immune Effector Cell-Associated Hemophagocytic Lymphohistiocytosis-Like Syndrome.

Single-cell Transcriptional Atlas of Human Hematopoiesis Reveals Genetic and Hierarchy-Based Determinants of Aberrant AML Differentiation

人类造血单细胞转录图谱揭示了异常急性髓系白血病分化的遗传和层级决定因素

DLBCL Cells Emerge after CD19 CAR T Cells with Cross-Antigen Resistance and a Gene Signature Predictive of Clinical CAR T-cell Response

DLBCL细胞在CD19 CAR T细胞治疗后出现，具有交叉抗原耐药性和可预测临床CAR T细胞反应的基因特征。

Dynamics of Mutant Hematopoietic Progenitor Cells Are Not Associated with Clinical Outcomes in Multiple Myeloma

突变造血祖细胞的动态变化与多发性骨髓瘤的临床结果无关

Enhancer Hijacking Discovery in Acute Myeloid Leukemia by Pyjacker Identifies MNX1 Activation via Deletion 7q

利用 Pyjacker 在急性髓系白血病中发现增强子劫持，揭示了 7q 缺失导致的 MNX1 激活。

Microbiota Shape Metabolic and Immune Determinants of CAR-T Therapy and Correlate with Outcomes in Myeloma

微生物群影响 CAR-T 疗法的代谢和免疫决定因素，并与多发性骨髓瘤的预后相关

SOCS1 Protects Acute Myeloid Leukemia against Allogeneic T Cell-Mediated Cytotoxicity

SOCS1保护急性髓系白血病免受同种异体T细胞介导的细胞毒性作用

B-cell Receptor Silencing Reveals the Origin and Dependencies of High-Grade B-cell Lymphomas with MYC and BCL2 Rearrangements

B细胞受体沉默揭示了具有MYC和BCL2重排的高级别B细胞淋巴瘤的起源和依赖性