Cell Genomics

A genome-scale single-cell CRISPRi map of trans gene regulation across human pluripotent stem cell lines.

Uncovering the signatures of aging and senescence in the human dorsolateral prefrontal cortex.

Spatial transcriptomics reveals altered communities and drivers of aberrant epithelia and pro-fibrotic fibroblasts in interstitial lung diseases.

Single-cell eQTL mapping reveals cell-type-specific genetic regulation in lung cancer.

单细胞eQTL定位揭示肺癌中细胞类型特异性基因调控。

Cellular senescence in human liver under normal aging and cancer.

正常衰老和癌症下人类肝脏细胞衰老。

Endogenous fine-mapping and prioritization of functional regulatory elements in complex genetic loci

复杂基因位点中功能调控元件的内源性精细定位和优先级排序

Coordinated regulation by lncRNAs results in tight lncRNA-target couplings

lncRNA的协同调控导致lncRNA与靶标之间紧密结合。

Temporal multi-omics analysis of COVID-19 in end-stage kidney disease

终末期肾病患者 COVID-19 的时间多组学分析

Disentangling cell-intrinsic and cell-extrinsic factors underlying evolution

厘清进化背后的细胞内在因素和细胞外在因素

Binding domain mutations provide insight into CTCF's relationship with chromatin and its contribution to gene regulation

结合域突变有助于深入了解CTCF与染色质的关系及其对基因调控的贡献。