Matrix-assisted laser desorption ionization-time of flight mass spectrometry identifies Pseudomonas aeruginosa high-risk clones

基质辅助激光解吸电离飞行时间质谱法鉴定铜绿假单胞菌高危克隆

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作者:Nadège Cabrolier, Marlène Sauget, Xavier Bertrand, Didier Hocquet

Abstract

We show here that matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) accurately and quickly identified the five high-risk clones of Pseudomonas aeruginosa sequence type 111 (ST111), ST175, ST235, ST253, and ST395. The use of this screening technique by clinical microbiology laboratories may tackle the spread of high-risk clones by the quick implementation of hygiene control procedures for relevant patients.

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