Crystal structure of (1'S,2'S,3S)-1'-benzoyl-2'-(4-meth-oxy-phen-yl)-1-methyl-2',5',6',10b'-tetra-hydro-1'H-spiro-[indoline-3,3'-pyrrolo-[2,1-a]isoquinolin]-2-one.

In the title spiro compound, C(34)H(30)N(2)O(3), the central pyrrolidine ring is fused with the tetra-hydro-iso-quinoline ring, both having distorted envelope conformations, with the flap atoms being C and N, respectively. The meth-oxy-phenyl group is attached to the pyrrolidine ring, and is disordered over two positions, with refined occupancies of 0.638†(6):0.362†(6)†à . The central pyrrolidine ring is inclined relative to the tetra-hydro-iso-quinoline group, such that the dihedral between the non-flap atoms of each ring system is 11.29†(7)°. The spiro-linkage creates a dihedral angle of 83.26†(5)° between the indolinone ring and the non-flap atoms of the pyrrolidine ring. In the crystal, mol-ecules are linked via C-H⋯O hydrogen bonds. For the major disorder component, these form C(11) chains that propagate parallel to the a axis.