Synthesis, crystal structure and Hirshfeld surface analysis of 4-[3-(4-hy-droxy-phen-yl)-4,5-di-hydro-1H-pyrazol-5-yl]-2-meth-oxy-phenol monohydrate.

4-[3-(4-羟基苯基)-4,5-二氢-1H-吡唑-5-基]-2-甲氧基苯酚一水合物的合成、晶体结构和Hirshfeld表面分析。

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In the title pyrazoline derivative, C(16)H(16)N(2)O(3)·H(2)O, the pyrazoline ring has an envelope conformation with the substituted sp (2) C atom on the flap. The pyrazoline ring makes angles of 86.73†(12) and 13.44†(12)° with the tris-ubstituted and disubstituted benzene rings, respectively. In the crystal structure, the mol-ecules are connected into chains running in the b-axis direction by O-H⋯N hydrogen bonding. Parallel chains inter-act through N-H⋯O hydrogen bonds and π-π stacking of the tris-ubstituted phenyl rings. The major contribution to the surface contacts are H⋯H contacts (44.3%) as concluded from a Hirshfeld surface analysis.

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