A high-throughput structural system biology approach to increase structure representation of proteins from Clostridioides difficile.

采用高通量结构系统生物学方法提高艰难梭菌蛋白质的结构表征。

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Clostridioides difficile causes life-threatening gastrointestinal infections. It is a high-risk pathogen due to a lack of effective treatments, antimicrobial resistance, and a poorly conserved genomic core. Herein, we report 30 X-ray structures from a structure genomics pipeline spanning 13 years, representing 10.2% of the X-ray structures for this important pathogen.

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