Nine polyketides, including two new benzophenone derivatives, peniphenone (1) and methyl peniphenone (2), along with seven known xanthones (3-9) were obtained from mangrove endophytic fungus Penicillium sp. ZJ-SYâ isolated from the leaves of Sonneratia apetala. Their structures were elucidated on the basis of MS, 1D, and 2D NMR data. Compounds 1, 3, 5, and 7 showed potent immunosuppressive activity with IC(50) values ranging from 5.9 to 9.3 μg/mL.
Polyketides with Immunosuppressive Activities from Mangrove Endophytic Fungus Penicillium sp. ZJ-SYâ.
来自红树林内生真菌 Penicillium sp. ZJ-SYâ‚‚. 的具有免疫抑制活性的聚酮化合物
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| 期刊： | Marine Drugs | 影响因子： | 5.400 |
| 时间： | 2016 | 起止号： | 2016 Nov 25; 14(12):217 |
| doi： | 10.3390/md14120217 | ||
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