Pitfalls Associated With the Use of Molecular Diagnostic Panels in the Diagnosis of Cryptococcal Meningitis

分子诊断试剂盒在隐球菌性脑膜炎诊断中的应用陷阱

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作者:Jane A O'Halloran,Alexander Franklin,William Lainhart,Carey-Ann Burnham,William Powderly,Erik Dubberke

Abstract

We report the case of a kidney transplantation patient on chronic immunosuppressive therapy presenting with subacute meningitis. The final diagnosis of cryptococcal meningitis was delayed due to 2 false-negative cryptococcal results on a molecular diagnostic panel. Caution with such platforms in suspected cryptococcal meningitis is needed.

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