Ultrasensitive Test Systems Are Required to Quantify Interferon Alpha Protein in Serum Samples.

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作者:Haljasmägi Liis, Meisalu Sandra, Bondet Vincent, Peterson Pärt, Duffy Darragh, Kisand Kai
Selecting a sensitive test system is crucial to measure IFNα in serum samples. Simoa digital ELISA stands out for its high sensitivity and strong correlation with transcript-based IFN-induced gene (ISG) scores. In SLE, the ISG score is explained by circulating IFNα levels with negligible contribution from IFNβ or IFNγ. Created in BioRender.

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