IRFinder-S: a comprehensive suite to discover and explore intron retention

IRFinder-S:一款用于发现和探索内含子保留的综合套件

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作者:Claudio Lorenzi #, Sylvain Barriere #, Katharina Arnold, Reini F Luco, Andrew J Oldfield, William Ritchie

Abstract

Accurate quantification and detection of intron retention levels require specialized software. Building on our previous software, we create a suite of tools called IRFinder-S, to analyze and explore intron retention events in multiple samples. Specifically, IRFinder-S allows a better identification of true intron retention events using a convolutional neural network, allows the sharing of intron retention results between labs, integrates a dynamic database to explore and contrast available samples, and provides a tested method to detect differential levels of intron retention.

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