Distinct populations of hepatic stellate cells in the mouse liver have different capacities for retinoid and lipid storage

小鼠肝脏中不同种类的肝星状细胞具有不同的类视黄酸和脂质储存能力

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作者:Diana N D'Ambrosio, José L Walewski, Robin D Clugston, Paul D Berk, Richard A Rippe, William S Blaner

Conclusion

Our observations suggest that the HSC population in a healthy, uninjured liver is heterogeneous. One subset of the total HSC population, which expresses early markers of HSC activation, may be "primed" and ready for rapid response to acute liver injury.

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