Eosin Y-Catalyzed Synthesis of 3-Aminoimidazo[1,2- a]Pyridines via the HAT Process under Visible Light through Formation of the C-N Bond

在可见光下通过 HAT 工艺通过形成 CN 键伊红 Y 催化合成 3-氨基咪唑并[1,2- a]吡啶

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作者:Himanshu Kumar Singh, Arsala Kamal, Savita Kumari, Dhirendra Kumar, Suresh Kumar Maury, Vandana Srivastava, Sundaram Singh

Abstract

A comfortable, environment-friendly, and metal-free approach for synthesizing the biologically important moiety aminoimidazopyridine through the multicomponent reaction of benzylamine, 2-aminopyridine, and t-butyl isocyanide under visible light using eosin Y as a photocatalyst has been developed. Inexpensive, nontoxic, the effortless accessibility of starting materials, and nonparticipation of particular glassware and a photoreactor system are important qualities of the current approach. Strangely, the mild conditions, environment-friendly, and enumerating tolerance of an extensive range of both electron-donating and electron-withdrawing groups are additional features of the approach.

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