Screening of Panamanian Plant Extracts for Pesticidal Properties and HPLC-Based Identification of Active Compounds

筛选巴拿马植物提取物的杀虫特性并利用 HPLC 进行活性化合物鉴定

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作者:Niels Guldbrandsen, Maria De Mieri, Mahabir Gupta, Tobias Seiser, Christine Wiebe, Joachim Dickhaut, Rüdiger Reingruber, Oliver Sorgenfrei, Matthias Hamburger

Abstract

A library of 600 taxonomically diverse Panamanian plant extracts was screened for fungicidal, insecticidal, and herbicidal activities. A total of 19 active extracts were submitted to HPLC-based activity profiling, and extracts of Bocconia frutescens, Miconia affinis, Myrcia splendens, Combretum aff. laxum, and Erythroxylum macrophyllum were selected for the isolation of compounds. Chelerythrine (2), macarpine (3), dihydrosanguinarine (5), and arjunolic acid (8) showed moderate-to-good fungicidal activity. Myricetin-3-O-(6''-O-galloyl)-β-galactopyranoside (13) showed moderate insecticidal activity, but no compound with herbicidal activity was identified.

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