The Effect of Exposure to Neighborhood Violence on Glucocorticoid Receptor Signaling in Lung Tumors

邻里暴力对肺癌糖皮质激素受体信号的影响

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作者:Hannah Heath, Jin Y Yoo, Sabrina Akter, Atharva Jain, Vani Sharma, Hannah McGee, Aiman Soliman, Abeer M Mahmoud, Alicia K Matthews, Robert A Winn, Zeynep Madak-Erdogan, Sage J Kim

Significance

Exposure to neighborhood violent crime is correlated with glucocorticoid signaling and lung tumor gene expression changes associated with increased tumor aggressiveness, suggesting social conditions have downstream biophysical consequences that contribute to lung cancer disparities.

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