Simulating Transplant Small-for-size Grafts Using Human Liver Monosegments: The Impact of Portal Perfusion Pressure

利用人肝单段模拟小体积移植:门静脉灌注压的影响

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作者:M Mohamed,L Kang,C Zhang,B Edenfield,J Sykes,T Brown,J L Johnson,F Rehman,J H Nguyen

Abstract

Small-for-size-liver grafts (SFSG) in adult transplant recipients have elevated risk of graft failure, limiting its application in clinical liver transplantation. Relevant preclinical model of SFSG is lacking. Relevant to deceased-donor split liver transplant and living-donor liver transplant in adult recipients, in this study, we present our initial characterization of SFSG model using monosegments of a discarded human donor liver.

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