Direct Conversion of Cord Blood CD34+ Cells Into Neural Stem Cells by OCT4

利用 OCT4 将脐带血 CD34+ 细胞直接转化为神经干细胞

阅读:18
作者:Wenbin Liao, Nick Huang, Jingxia Yu, Alexander Jares, Jianchang Yang, Gary Zieve, Cecilia Avila, Xun Jiang, Xiao-Bing Zhang, Yupo Ma

Significance

This study describes a novel method to generate expandable induced neural stem cells from human cord blood cells in a feeder-free system by a single factor, OCT4. The data are promising for future applications that require the generation of large amounts of autologous neural stem cells in disease modeling and regenerative medicine.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。