High prevalence of SARS-CoV-2 antibodies and low prevalence of SARS-CoV-2 RNA in cats recently exposed to human cases

在近期接触人类病例的猫中,SARS-CoV-2 抗体的流行率很高,而 SARS-CoV-2 RNA 的流行率很低

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作者:Laurence Daigle, Hattaw Khalid, Carl A Gagnon, Julie Arsenault, Dorothee Bienzle, Sarah-Kim Bisson, Marie-Claude Blais, José Denis-Robichaud, Caroline Forest, Valérie Grenier St-Sauveur, Marika Koszegi, Jennifer MacNicol, Nicolas Nantel-Fortier, Charlotte Nury, Natalie Prystajecky, Erin Fraser #, Hé

Background

The primary

Conclusions

We showed that cats develop antibodies to SARS-CoV-2 when exposed to recent human cases, but detection of viral RNA on swabs is rare, even when sampling occurs soon after confirmation of a human case. Moreover, cats with detectable levels of virus showed clinical signs more often than cats without signs, which can be useful for the management of such cases.

Results

Nine (0.16; 95% BCI = 0.08-0.28) and 38 (0.69; 95% BCI = 0.56-0.80) cats had at least one positive RT-qPCR and at least one positive serological test result, respectively. No risk factor was associated with the prevalence of SARS-CoV-2 serum antibodies. The prevalence of clinical signs suggestive of COVID-19 in cats, mainly sneezing, was 2.12 (95% BCI = 1.03-3.98) times higher amongst cats with detectable viral RNA compared to those without. Conclusions: We showed that cats develop antibodies to SARS-CoV-2 when exposed to recent human cases, but detection of viral RNA on swabs is rare, even when sampling occurs soon after confirmation of a human case. Moreover, cats with detectable levels of virus showed clinical signs more often than cats without signs, which can be useful for the management of such cases.

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