The Importance of Extracellular Vesicle Screening in Gastric Cancer: A 2024 Update

细胞外囊泡筛查在胃癌中的重要性:2024 年更新

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作者:Vasile Bintintan, Claudia Burz, Irena Pintea, Adriana Muntean, Diana Deleanu, Iulia Lupan, Gabriel Samasca

Abstract

Extracellular vesicles, or EVs, are membrane-bound nanocompartments produced by tumor cells. EVs carry proteins and nucleic acids from host cells to target cells, where they can transfer lipids, proteomes, and genetic material to change the function of target cells. EVs serve as reservoirs for mobile cellular signals. The collection of EVs using less invasive processes has piqued the interest of many researchers. Exosomes carry substances that can suppress the immune system. If the results of exosome screening are negative, immunotherapy will be beneficial for GC patients. In this study, we provide an update on EVs and GC based on ongoing review papers and clinical trials.

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